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The application of biological clean rooms is becoming more and more widespread. Clean rooms of the same level have very different requirements due to different application fields. Different types of biological clean rooms must comply with corresponding specifications. If you do not understand these specifications, you cannot design and construct them. The basic ideas of laboratory design are economic and practical. The laboratory design includes change room, air shower, buffer room and other pre-experimental preparations. The principle of separation of people and logistics is adopted to reduce experimental contamination and ensure safety.

 

 Classification of biological laboratory clean room

Laboratory classification processing objects

Level 1: It is less harmful to the human body, animals and plants, or the environment, and does not have pathogenic factors that can cause disease to healthy adults, animals and plants.

Level 2: Pathogenic factors that are moderately harmful or potentially dangerous to humans, animals, plants, or the environment, but will not cause serious harm to healthy adults, animals, plants, and the environment. There are effective prevention and treatment measures.

Level 3: Pathogenic factors that are highly dangerous to human body, animals, plants, or environment. They can infect people with serious or even fatal diseases mainly through aerosols, or are highly harmful to animals, plants and environment. There are usually preventive treatments.

Level 4: Highly dangerous to human body, animals, plants or environment, is transmitted through aerosols or the transmission route is unknown, or is an unknown, dangerous pathogenic factor. There are no preventive treatments.

 

 Composition of biological laboratory clean room

The construction plan of the biological laboratory clean room includes: cleanroom building layout and decoration, air conditioning, water supply and drainage, gas supply, electrical design, centralized control, security, construction technology, testing, training and other aspects, especially the following aspects of the plan with several aspects need to be fully considered.

1. Cleanroom building layout and decoration plan: It is the basis for the safe operation of biological laboratory clean room. Due to the dangers of microbial germs, it is necessary to prevent dangerous microorganisms from spreading to outside world, comprehensively block the contact between dangerous microorganisms and the external environment, and at the same time prevent microorganisms from being contaminated by the outside world, which will affect the accuracy of experimental results. Reasonable laboratory measures must be taken layout and decoration scheme. The laboratory layout is reasonably divided into clean areas, semi-contaminated areas and contaminated areas according to safety requirements. Special passages are set up for people and objects respectively, necessary buffer rooms are set up, and measures such as primary isolation and secondary isolation are adopted to effectively avoid crossover, contamination and fundamentally prevent the spread of dangerous microorganisms; laboratory decoration uses reliable materials and reasonable construction measures to ensure that biological laboratory clean room is always in a relatively sealed environment, preventing the escape of microorganisms and making it easy to clean and disinfect the laboratory. At the same time, avoid external damage to the laboratory environment.

2. Cleanroom HVAC system: It is the key to the safe operation of biological laboratory clean room. Since the operating objects in the biological laboratory clean room are dangerous microorganisms that are harmful to the human body, animals, plants, or environment, it is necessary to adopt a reasonable heating and ventilation system to maintain the relatively negative pressure environment of the biological laboratory clean room and not be destroyed at any time to ensure that dangerous microorganisms in laboratory cannot spread to the external environment. The air conditioning system must operate reliably, use advanced technology, rationally utilize and save energy and resources, ensure the quality and safety of the environment, provide the required temperature and humidity for experimental personnel, and ensure that biological experiments are conducted under safe conditions to ensure that experiments results must be accurate. At the same time, it must also control the cleanliness of the laboratory clean room and filter the fresh air so that the laboratory clean room can meet certain purification requirements. Among them, the exhaust system is the key point, playing an important role in ensuring a relatively negative pressure environment in laboratory clean room and effectively filtering indoor polluted exhaust air.

3. Cleanroom control system: It is the nerve center for the safe operation of the entire biological laboratory clean room. Since the experimental subjects of the biological laboratory clean room are dangerous microorganisms, due to the principle of strict pollution control, it requires the minimum number of maintenance personnel and the use of optimized management and maintenance methods to monitor the location of the equipment in each laboratory clean room in real time. The physical environment ensures that the laboratory clean room is always in a relatively negative pressure environment during operation to prevent the leakage of dangerous microorganisms.

4. Testing plan: It is the guarantee for the long-term safe operation of the biological laboratory clean room. Due to the particularity of the biological laboratory clean room, in addition to strict design, construction, and debugging, in order to ensure its safety, it must undergo necessary engineering testing and strict acceptance. It can only be put into operation after meeting the safety requirements and usage requirements. In addition, some factors during use, such as non-professional management and use, replacement of hepa filters, etc will have an impact on the safety of the laboratory clean room. Therefore, regular testing during use is equally important.

5. Training program: Since experimental personnel in biological laboratory clean room are usually medical experts and may not necessarily have a good understanding of the principles of the entire laboratory clean room system, the training program allows all laboratory staff to understand the characteristics of the entire system and master its operating rules. The safety hazards can be discovered in time, and corresponding emergency measures can be made in a timely manner to control the further deterioration of the situation, which is of great help in easing the difficulty of subsequent maintenance work.

 

 Characteristics of biological laboratory clean room

The overall solution for biological laboratory clean room is different from general laboratory engineering or cleanroom engineering according to the safety requirements and usage requirements of the laboratory. With its deep understanding of user needs, superb team of consultants and engineering design and construction experts, and advanced planning and operation concepts, it has formed a complete set of biological laboratory cleanroom solutions. It has the characteristics of high security, specialization, integrity, modularity and standardization.

1. High safety: The entire biological laboratory clean room construction process is carried out under the overall arrangement of the company, which unifies the opinions of all parties and eliminates the lack of safety in construction process due to inconsistent opinions in the design and construction processes. Disadvantages such as hidden dangers and rework ensure the rigor of the biological laboratory clean room so that it can operate safely for a long time.

2. Specialization: We have many years of experience in serving users in the industry. It is managed by unified coordination, from early planning and site selection, design and construction, commissioning and operation, to lifelong maintenance services, with professional biological laboratory cleanroom engineering design and construction. Expert services, experienced project management personnel, standardized processes, and large-scale operations allow users to fully experience the consistent high quality and unique advantages of system configuration, overall implementation, and expert services as a professional company.

3. Integrity: The integral biosafety laboratory clean room provides customers with a one-stop cleanroom project, which reduces procurement costs and large investment in energy, material resources and manpower. With the overall biological laboratory cleanroom solutions, systematic equipment configuration ensures the capacity of the entire biological laboratory clean room and the matching of equipment to meet current and future development needs. In addition, we provide users with permanent contract services, ensuring that users receive long-term and even lifelong service maintenance, and fully ensuring the maximum benefits of customer investment.

4. Modularization: When designing solutions for biological laboratory clean room users, we adopt industrialized and standardized operation concepts to summarize and organize many years of cleanroom engineering projects. This is to modularize complex biological laboratory clean room so that they can be appropriately adapted to the needs of users. A more optimized combination of different situations, characteristics and needs. In the solutions provided, we adopt the approach of adapting measures to local conditions, making building decoration, power distribution, air conditioning, and fire protection all into standardized plans, and formulating targeted plan designs.

5. Standardization: All program design, equipment and material procurement, construction project management, and quality supervision services for the overall biological laboratory clean room are provided by the design and project management personnels, and serve as the design plan for the overall biological laboratory clean room, we hope to achieve a standardized design of the plan, adopt consistent design ideas and achieve unified style and quality.

 

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